Publications

Postprandial macrophage-derived IL-1β stimulates insulin, and both synergistically promote glucose disposal and inflammation.

Dror E, Dalmas E, Meier DT, Wueest S, Thévenet J, Thienel C, Timper K, Nordmann TM, Traub S, Schulze F, Item F, Vallois D, Pattou F, Kerr-Conte J, Lavallard V, Berney T, Thorens B, Konrad D, Böni-Schnetzler M, Donath MY.Nat Immunol. 2017 Mar;18(3):283-292. doi: 10.1038/ni.3659. Epub 2017 Jan 16.PMID: 28092375 Free article.

The cephalic phase of insulin release is modulated by IL-1β.

Wiedemann SJ, Trimigliozzi K, Dror E, Meier DT, Molina-Tijeras JA, Rachid L, Le Foll C, Magnan C, Schulze F, Stawiski M, Häuselmann SP, Méreau H, Böni-Schnetzler M, Donath MY.Cell Metab. 2022 Jul 5;34(7):991-1003.e6. doi: 10.1016/j.cmet.2022.06.001. Epub 2022 Jun 23.PMID: 35750050 Free article.

Epigenetic dosage identifies two major and functionally distinct β cell subtypes.

Dror E, Fagnocchi L, Wegert V, Apostle S, Grimaldi B, Gruber T, Panzeri I, Heyne S, Höffler KD, Kreiner V, Ching R, Tsai-Hsiu Lu T, Semwal A, Johnson B, Senapati P, Lempradl A, Schones D, Imhof A, Shen H, Pospisilik JA.Cell Metab. 2023 May 2;35(5):821-836.e7. doi: 10.1016/j.cmet.2023.03.008. Epub 2023 Mar 21.PMID: 36948185 Free PMC article.

Glucosamine links hyperglycemia to mTORC1 activation and glucose toxicity in diabetes.

Riahi Y, Kogot-Levin A, Teselpapa Z, Zemelman E, Gamal F, Cohen T, Nasereddin A, Shiff I, Abramovich I, Agranovich B, Avrahami D, Hinden L, Cerasi E, Kaur D, Grinberg L, Piran R, Tam J, Bernal-Mizrachi E, Dror E, Leibowitz G.JCI Insight. 2026 May 22;11(10):e197331. doi: 10.1172/jci.insight.197331. eCollection 2026 May 22.PMID: 42171606 Free PMC article.